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0 0.5 1 1.5 2+ Viral clearance 86% Improvement Relative Risk c19pvpi.com Mohamed et al. Povidone-Iod.. for COVID-19 RCT EARLY Favors povidone-iodine Favors control
Mohamed, 10 patient povidone-iodine early treatment RCT: 86% improved viral clearance [p=0.17] https://c19p.org/mohamed
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Early viral clearance among COVID-19 patients when gargling with povidone-iodine and essential oils: a pilot clinical trial
Mohamed et al., medRxiv, doi:10.1101/2020.09.07.20180448 (Preprint)
9 Sep 2020    Source   PDF   Share   Tweet
Tiny RCT with 5 PVP-I patients, gargling 30 seconds, 3x per day, and 5 control patients (essential oils and tap water were also tested), showing improved viral clearance with PVP-I.
risk of no viral clearance, 85.7% lower, RR 0.14, p = 0.17, treatment 0 of 5 (0.0%), control 3 of 5 (60.0%), NNT 1.7, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm), day 12.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Mohamed et al., 9/9/2020, Randomized Controlled Trial, Malaysia, Europe, preprint, 16 authors.
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