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00.250.50.7511.251.51.752+Mohamed (RCT)86%0.14 [0.01-2.21]viral+0/53/5Improvement, RR [CI]TreatmentControlChoudhury (RCT)88%0.12 [0.03-0.50]death2/30317/303Guenezan (RCT)63%0.37 [0.06-1.63]viral load1212Arefin (RCT)79%0.21 [0.08-0.54]viral+4/2719/27Tau​2 = 0.00; I​2 = 0.0%Early treatment82%0.18 [0.09-0.38]6/34739/34782% improvementSeet (CLUS. RCT)45%0.55 [0.38-0.80]severe case42/73564/619OT​1Improvement, RR [CI]TreatmentControlTau​2 = 0.00; I​2 = 0.0%PEP45%0.55 [0.38-0.80]42/73564/61945% improvementAll studies71%0.29 [0.14-0.61]48/1,082103/96671% improvement5 povidone-iodine COVID-19 studiesc19pvpi.com 6/17/211 OT: comparison with other treatmentTau​2 = 0.30; I​2 = 47.5%; Z = 3.24 (p = 0.00059)Lower RiskIncreased Risk 00.250.50.7511.251.51.752+Choudhury (RCT)88%0.12 [0.03-0.50]2/30317/303Improvement, RR [CI]TreatmentControlTau​2 = 0.00; I​2 = 0.0%Early treatment88%0.12 [0.03-0.50]2/30317/30388% improvementAll studies88%0.12 [0.03-0.50]2/30317/30388% improvement1 povidone-iodine COVID-19 mortality resultc19pvpi.com 6/17/21Tau​2 = 0.00; I​2 = 0.0%; Z = 2.88 (p = 0.002)Lower RiskIncreased Risk 00.250.50.7511.251.51.752+Choudhury (RCT)86%0.14 [0.03-0.62]hosp.2/30314/303Improvement, RR [CI]TreatmentControlTau​2 = 0.00; I​2 = 0.0%Early treatment86%0.14 [0.03-0.62]2/30314/30386% improvementAll studies86%0.14 [0.03-0.62]2/30314/30386% improvement1 povidone-iodine COVID-19 hospitalization resultc19pvpi.com 6/17/21Tau​2 = 0.00; I​2 = 0.0%; Z = 2.59 (p = 0.0048)Lower RiskIncreased Risk 00.250.50.7511.251.51.752+Seet (CLUS. RCT)31%0.69 [0.37-1.01]338/735433/619OT​1Improvement, RR [CI]TreatmentControlTau​2 = 0.00; I​2 = 0.0%PEP31%0.69 [0.37-1.01]338/735433/61931% improvementAll studies31%0.69 [0.63-0.76]338/735433/61931% improvement1 povidone-iodine COVID-19 case resultc19pvpi.com 6/17/211 OT: comparison with other treatmentTau​2 = 0.00; I​2 = 0.0%; Z = 7.77 (p < 0.0001)Lower RiskIncreased Risk 00.250.50.7511.251.51.752+Choudhury (RCT)88%0.12 [0.03-0.50]death2/30317/303Improvement, RR [CI]TreatmentControlTau​2 = 0.00; I​2 = 0.0%Early treatment88%0.12 [0.03-0.50]2/30317/30388% improvementSeet (CLUS. RCT)45%0.55 [0.38-0.80]severe case42/73564/619OT​1Improvement, RR [CI]TreatmentControlTau​2 = 0.00; I​2 = 0.0%PEP45%0.55 [0.38-0.80]42/73564/61945% improvementAll studies70%0.30 [0.07-1.32]44/1,03881/92270% improvement2 povidone-iodine COVID-19 serious outcomesc19pvpi.com 6/17/211 OT: comparison with other treatmentTau​2 = 0.90; I​2 = 75.4%; Z = 1.59 (p = 0.056)Lower RiskIncreased Risk 00.250.50.7511.251.51.752+Mohamed (RCT)86%0.14 [0.01-2.21]viral+0/53/5Improvement, RR [CI]TreatmentControlChoudhury (RCT)88%0.12 [0.03-0.50]death2/30317/303Choudhury (RCT)86%0.14 [0.03-0.62]hosp.2/30314/303Choudhury (RCT)96%0.04 [0.02-0.07]viral+8/303213/303Guenezan (RCT)63%0.37 [0.06-1.63]viral load1212Arefin (RCT)79%0.21 [0.08-0.54]viral+4/2719/27Arefin (RCT)89%0.11 [0.03-0.41]viral+2/2719/27Arefin (RCT)53%0.47 [0.26-0.85]viral+9/2719/27Arefin (RCT)80%0.20 [0.09-0.44]viral+5/2725/27Arefin (RCT)64%0.36 [0.21-0.62]viral+9/2725/27Arefin (RCT)74%0.26 [0.19-0.37]viral+29/13544/54Seet (CLUS. RCT)45%0.55 [0.38-0.80]severe case42/73564/619OT​1Seet (CLUS. RCT)31%0.69 [0.37-1.01]cases338/735433/619OT​1povidone-iodine COVID-19 outcomesc19pvpi.com 6/17/21Lower RiskIncreased Risk
Please send us corrections, updates, or comments. Vaccines and treatments are both extremely valuable and complementary. All practical, effective, and safe means should be used. Elimination of COVID-19 is a race against viral evolution. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. Denying the efficacy of any method increases the risk of COVID-19 becoming endemic; and increases mortality, morbidity, and collateral damage. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. Treatment protocols for physicians are available from the FLCCC.
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