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0 0.5 1 1.5 2+ Fold change 33% Improvement Relative Risk c19pvpi.com Seneviratne et al. Povidone-Iod.. for COVID-19 RCT LATE Favors povidone-iodine Favors control
Seneviratne, 6 patient povidone-iodine late treatment RCT: 33% improved viral clearance [p=0.01] https://c19p.org/seneviratne
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Efficacy of commercial mouth-rinses on SARS-CoV-2 viral load in saliva: randomized control trial in Singapore
Seneviratne et al., Infection, doi:10.1007/s15010-020-01563-9
14 Dec 2020    Source   PDF   Share   Tweet
Small mouthwash RCT with 4 PVP-I patients and 2 water patients concluding that PVP-I may have a sustained effect on reducing the salivary SARS-CoV-2 level in COVID-19 patients. ISRCTN95933274.
relative fold change, 32.9% better, RR 0.67, p < 0.01, treatment 4, control 2, PVP-I vs. water, 6 hours.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Seneviratne et al., 12/14/2020, Randomized Controlled Trial, Singapore, Asia, peer-reviewed, 12 authors.
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This PaperPovidone-Iod..All
Late treatment
is less effective
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