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0 0.5 1 1.5 2+ Improvement in Ct value 89% Improvement Relative Risk c19pvpi.com Elzein et al. Povidone-Iod.. for COVID-19 RCT EARLY Favors povidone-iodine Favors control
Elzein, 34 patient povidone-iodine early treatment RCT: 89% improved viral clearance [p=0.05] https://c19p.org/elzein
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In vivo evaluation of the virucidal efficacy of chlorhexidine and povidone-iodine mouthwashes against salivary SARS-CoV-2. A randomized-controlled clinical trial
Elzein et al., Journal of Evidence Based Dental Practice, doi:10.1016/j.jebdp.2021.101584 (date from earlier preprint)
17 Mar 2021    Source   PDF   Share   Tweet
Small RCT comparing mouthwashing with PVP-I, Chlorhexidine, and water, showing significant efficacy for both PVP-I and Chlorhexidine, with PVP-I increasing Ct by a mean of 4.45 (p < 0.0001) and Chlorhexidine by a mean of 5.69 (p < 0.0001), compared to no significant difference for water.
relative improvement in Ct value, 88.8% better, RR 0.11, p < 0.05, treatment 25, control 9.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Elzein et al., 17 Mar 2021, Double Blind Randomized Controlled Trial, Lebanon, peer-reviewed, 7 authors.
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